This paper investigated the association between unemployment and human security provisioning using ordinary least square estimator of regression analysis. The outcomes of the study show that food security has an inverse relationship with youth unemployment in the Gambia while purchasing power parity has a significant effect on unemployment rate in Nigeria. In both countries, there is a high positive association between youth unemployment and human security provisioning. Moreover, the study found empirically that the key factor responsible for youth vulnerability is lack of subsistence occasioned by unemployment. Therefore, it has become more pertinent that the government of Nigeria and the Gambia develop a pragmatic approach in reducing youth unemployment as a strategy for reducing the incidence of human trafficking.